The way I was trying to set it up was to be able to have a Game Object with a GUI component with the 9-slice texture applied to a Box node positioned at 0,0. Then I was going to try and create a factory that would instantiate multiple Game Objects (and therefore multiple GUIs) offset from each other to create a grid of the 9-slice box nodes.
As a test to see if I could move the GUI with the game object, I tried adding a single instance directly to the main collection and offset the position. It looked correct in the editor, but building it shifted the interface back to its original position.