My laptop has built-in graphics (Intel HD graphics 520) and a dedicated graphics card (Radeon R7 M370).
When running Windows native builds for any of my games, they all run slowly (~30fps). If I disable the dedicated graphics card in device manager, the games run perfectly fine at 60fps.
HTML5 builds are not affected.
Possibly some sort of conflict - not a huge issue for me but a heads-up nonetheless.