I think @Alex_8BitSkull used native extension for raycasts or AABB in Void Scrappers - and I think VS is a great benchmark with thousands of enemies on screen, so I think this is not that much of an issue actually 
As @britzl mentioned above, it’s not necessary, but you have an option to write your game in C++ as a native extension - for this check out what @sergey.lerg is doing - making a whole game in C++ in Defold (but he is generally a magician and uses also Lua for game data and Godot for some other magic 
)
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