I highly recommend that you try/test it yourself. It’s hard to know what you mean when you say ‘fairly good.’
It’s easier to get started if you don’t need lights, shadows, PBR materials and complex models. You can simply use unlit shaders, which are straightforward and as easy as 2D.
But when those things come into play, it becomes harder to get started. You’ll need to understand the shader, render script, etc., and you’ll start hitting the bumps.
Few games/assets that I know developed using Defold:
These are from @d954mas and he is working on a new game: x.com
https://poki.com/en/g/punch-legend-simulator
https://poki.com/en/g/blocky-universe
Old game from Defold showcase:
@aglitchman is working on a 3D game:
https://x.com/aglitchman/status/1882514044558745665
his asset:
There are the assets from @astrochili :
@Dragosha has a lots of 2D+3D prototypes:
https://x.com/dragosha
@Pawel released this last year for game jam:
I have an example project(wip) for one of my Defold extension
And these are the pixel art shaders which I recently release:
https://selimanac.github.io/defold-pixelart-shader-example/
https://selimanac.github.io/defold-pixelart-shader/
Other protoype pf mine:
https://x.com/selimanac/status/1864001615700644156