Great! Please work with the Defold team to create a Nintendo Switch support, I think they all are very interested.
For physics - you can use my Box2D extension, which removes most of the limitations of the built-in physics.
Sprites and 16 input sources - you just have to have a single input manager and distribute all the inputs manually. I do it in my games with automatic z sorting so that clicks go to the top objects first.
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