That’s exactly what I proposed in my Defork! I’m proud that similar solutions are used, Twine+Twinson is really a powerful tool
So, it looks like your story could be pretty nonlinear, is that true?
I’m really enjoying Twine, and the extensions saved my life! I had already designed my dialogue system before finding out about Defork, so I found it easier to just re-invent the wheel 
And yes, non-linearity is quite key to the story. The endings vary depending on your choices, you can fail/succeed in rescuing your friends, and of course NPCs end up in different situations depending on what you choose. Saving in the game is automatic, so there is no save-scumming. (Scary? Yes. Frustrating? Hopefully not!).